General Cell Based Assays
Eurofins Discoverx PathHunter eXpress VIPR1 Activated GPCR Internalization Assay, 2pl Kit. (93-0739E3CP5M)
The PathHunter VIPR1 Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of VIPR1 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged VIPR1. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting VIPR1-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress cyno CXCR2 HEK 293 β-Arrestin GPCR Assay, 10pl Kit. (93-0981E1CCP0L)
The PathHunter cyno CXCR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CXCL8/IL8) based activation of cyno CXCR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged cyno CXCR2 and EA-tagged β-Arrestin-2. Activation of cyno CXCR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Cynomolgus monkey version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cell Signaling Technology PathScanR Phospho-AMPK-alpha Thr172 Sandwich ELISA Kit 20 Kit
PathScanR Phospho-AMPK-alpha Thr172 Sandwich ELISA Kit 20 Kit
Cytek Biosciences Inc Mu TBNK Myeloid Treg Kit P
Product Name: Cytek Tonbo Mouse TBNK/Myeloid/Treg Kit
Cytek Catalog Number: 95-K001-T025
Product Class: Kits and Panels
Type: Panel
Size: 25 Tests
Revvity Health Sciences Inc HTRF cAMP Gs Dynamic Detection Kit, 20,000 Assay Points
HTRF cAMP Gs Dynamic Detection Kit, 20,000 Assay Points
Revvity Health Sciences Inc HTRF mAb Anti-GST XL665-Conjugate, 5,000 Assay Points
HTRF mAb Anti-GST XL665-Conjugate, 5,000 Assay Points
Eurofins Discoverx PathHunter eXpress DDR1 Functional Assay, 2-Plate Kit. (93-0894E3CP16M)
The PathHunter eXpress DDR1 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated DDR1 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged DDR1 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress rHTR2C U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0915E3RCP0L)
The PathHunter rHTR2C eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. serotonin) based activation of rHTR2C GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rHTR2C and EA-tagged β-Arrestin-2. Activation of rHTR2C stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Insulin Ultra Sensitive Detection Kit, 500 Assay Points
HTRF Insulin Ultra Sensitive Detection Kit, 500 Assay Points